Association of GSK3B With Alzheimer Disease and Frontotemporal Dementia
نویسندگان
چکیده
منابع مشابه
Association of GSK3B with Alzheimer disease and frontotemporal dementia.
BACKGROUND Deposits of abnormally hyperphosphorylated tau are a hallmark of several dementias, including Alzheimer disease (AD), and about 10% of familial frontotemporal dementia (FTD) cases are caused by mutations in the tau gene. As a known tau kinase, GSK3B is a promising candidate gene in the remaining cases of FTD and in AD, for which tau mutations have not been found. OBJECTIVE To exami...
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ژورنال
عنوان ژورنال: Archives of Neurology
سال: 2008
ISSN: 0003-9942
DOI: 10.1001/archneur.65.10.1368